Oosterzele is a municipality located in the Flemish province of East Flanders, in Belgium. The municipality comprises the towns of Balegem, Gijzenzele, Landskouter, Moortsele, Oosterzele proper and Scheldewindeke. On January 1, 2006 Oosterzele had a total population of 13,172. The total area is 43.12 km² which gives a population density of 305 inhabitants per km².