Melo is the capital city of the Cerro Largo Department of north-eastern Uruguay. It is located at the centre of the department, on the intersection of Route 7 with Route 8, 60 kilometres (37 mi) south of Aceguá and the border with Brazil. Other primary roads to the city are Route 26 and Route 44. The stream Arroyo Conventos (a tributary of Tacuarí River) flows by the west limits of the city.