Czyżew is a town in Wysokie Mazowieckie County, Podlaskie Voivodeship, in north-eastern Poland. It is the seat of the gmina (administrative district) called Gmina Czyżew. It lies approximately 19 kilometres (12 mi) south-west of Wysokie Mazowieckie and 67 km (42 mi) south-west of the regional capital Białystok.